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Nuevocor

Clinical-stage A*STAR spin-out developing mechanobiology-centered genetic medicines for cardiomyopathies; lead candidate NVC-001 is an AAV gene therapy for LMNA-related dilated cardiomyopathy, cleared by the FDA IND in 2025 and advancing into a Phase 1/2 trial.

Headquarters

Singapore / Paris, France / Philadelphia, USA

Year Founded

2021

Founders

Yann Chong Tan, Yin Loon Lee, Brian Burke, Colin Stewart, Mark Kay

Country

Singapore

Financial Information

Funding Stage

Series B

Recent Funding

$80.6M

Funding By

Kurma Partners, Angelini Ventures, EDBI, ClavystBio, Boehringer Ingelheim Venture Fund

Core Technology

PrOSIA mechanobiology platform with AAV gene therapy delivery

Product Type

Gene Therapy

Pipeline Stage (Very Important)

Phase I/II (IND cleared)

Regulatory Status

  • IND Filed: Yes
  • FDA/EMA Status: FDA IND cleared (2025)
  • Clinical Trial Registration: Phase 1/2 NVC-001 in LMNA-related dilated cardiomyopathy (planned)
  • Patents / IP Status: Filed (mechanobiology and gene therapy IP from A*STAR and Stanford)

Partnerships

Pharma Collaborations

Boehringer Ingelheim Venture Fund (investor)

Academic / Hospital Tie-ups

A*STAR (spin-out origin), Stanford University

CRO/CDMO Partnerships

None disclosed

Market & Differentiation

Targets the biomechanical cause rather than replacing the gene, aiming for a one-time therapy